A Colour Atlas of Removable Partial Dentures by J.C. Davenport;R. M. Basker;J.R. Heath;J.P. Ralph

By J.C. Davenport;R. M. Basker;J.R. Heath;J.P. Ralph

A realistic survey of detachable partial dentures, of curiosity to dentists and oral surgeons. themes coated comprise sufferer evaluate, partial denture layout, practise of the mouth and prosthetic therapy.

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Upper left panel, Depiction of neurovascular unit dis- playing relationships between neurons and their supply capillaries. (From del Zoppo GJ: Stroke and neurovascular protection. ) Upper right panel, Capillary from rat inferior colliculus. Note endothelial cell, basal lamina matrix, and surrounding astrocyte end-foot. 0 μm diameter. (Courtesy of Dr. C. ) Lower left panel, Post-capillary venule from rat cortex. ≈10 μm diameter. (Courtesy of J. H. ) Lower right panel, Key to the lower left panel, indicating the endothelium (endo), basal lamina matrix (arrowheads), astrocyte and astrocyte end-feet (A), and pericytes (*).

Weiss N, Zhang YY, Heydrick S, et al: Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction, Proc Natl Acad Sci U S A 98:12503–12508, 2001. Pelligrino DA, Koenig HM, Wang Q, et al: Protein kinase C suppresses receptor-mediated pial arteriolar relaxation in the diabetic rat, Neuroreport 5:417–420, 1994. Mayhan WG: Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus, Am J Physiol 256:H621–625, 1989.

Later, as after MCAO, the surviving microvasculature provides a scaffold for receptors and their ligands known to promote angiogenesis. 163,164 It has been proposed that induction of angiogenesis following MCAO results from local hypoxia. Low tissue O2 leads to inhibition of the degradation of hypoxiainducible factor-1 (HIF-1). 167-170 Their interaction results in endothelial cell expression of integrin αvβ3. 173,174 There is a robust literature on pericyte migration during angiogenesis. 175 However, if recovery is inhibited at the termination of angiogenesis by increased VEGF, then vascular regression can occur.

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